RNA Processing and Degradation in Bacillus subtilis
نویسندگان
چکیده
منابع مشابه
RNA processing and degradation in Bacillus subtilis.
This review focuses on the enzymes and pathways of RNA processing and degradation in Bacillus subtilis, and compares them to those of its gram-negative counterpart, Escherichia coli. A comparison of the genomes from the two organisms reveals that B. subtilis has a very different selection of RNases available for RNA maturation. Of 17 characterized ribonuclease activities thus far identified in ...
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Bacterial RNA degradation often begins with conversion of the 5'-terminal triphosphate to a monophosphate, creating a better substrate for subsequent ribonuclease digestion. For example, in Bacillus subtilis and related organisms, removal of the gamma and beta phosphates of primary transcripts by the RNA pyrophosphohydrolase RppH triggers rapid 5'-exonucleolytic degradation by RNase J. However,...
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Toxin-antitoxin (TA) modules are pairs of genes in which one member encodes a toxin that is neutralized or whose synthesis is prevented by the action of the product of the second gene, an antitoxin, which is either protein or RNA. We now report the identification of a TA module in the chromosome of Bacillus subtilis in which the antitoxin is an antisense RNA. The antitoxin, which is called RatA...
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Regulation of the cell-specific transcription factor sigma(F) in the spore-forming bacterium Bacillus subtilis involves the antisigma factor SpoIIAB. Contributing to the activation of sigma(F) is the degradation of SpoIIAB in a manner that depends on the protease ClpCP. Here we show that the three residues (LCN) located at the extreme C terminus of SpoIIAB are both necessary and sufficient for ...
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Mutants of Bacillus subtilis deficient in urocanase or in imidazolonepropionate hydrolase were isolated. These mutants are unable to use L-histidine as source of carbon or nitrogen for growth. The enzymes are thus essential for the metabolism of histidine. The structural genes specifying these enzymes are closely linked to those specifying the other two enzymes essential for histidine degradati...
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ژورنال
عنوان ژورنال: Microbiology and Molecular Biology Reviews
سال: 2003
ISSN: 1092-2172,1098-5557
DOI: 10.1128/mmbr.67.2.157-174.2003